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1.
Journal of Sun Yat-sen University(Medical Sciences) ; (6): 467-471, 2018.
Article in Chinese | WPRIM | ID: wpr-712976

ABSTRACT

[Objective] To determine the efficacy and safety of local injections of botulinum toxin A in the treatment of androgenetic alopecia.[Methods] 72 male patients were randomly into botulinum toxin An group (n=35) and the control group (n=37),the treatment time was 6 months.All the patients were photographed and evaluated,before the treatment,and 3 months and 6 months.[Results] After the treatment of half a year,a good result was observed,the hair density in the treatment group was higher after 3months and 6 months than before the treatment (P<0.05),but there was no difference between the after 3months and 6 months (P>0.05),the hair density in the control group was higher after 6 months than before the treatment and after 3 months (P<0.05),but there was no difference between the after 3 months and before the treatment (P>0.05);but there was no difference between the after 3 months and 6 months (P>0.05);After 6 months,the effective ratio and in two group were 91.4% and 86.5% in treated group,it showed no significant difference (P>0.05) [Conclusion] the treatment of local injections of botulinum toxin A has a marked effect on androgenetic alopecia,it is safe and effective.

2.
Journal of Sun Yat-sen University(Medical Sciences) ; (6): 157-160, 2018.
Article in Chinese | WPRIM | ID: wpr-712928

ABSTRACT

[Objective]To determine the efficacy and safety of 1064nm Q-switched laser combined with drug therapy in the treatment of mild to moderate rosacea.[Methods]73 patients with mild to moderate rosacea were divided into two groups randomly.The treatment group including 37 patients were treated with Q-switched laser combined with drug thera-py,the control group including 36 patients were treated with drug therapy only.Efficacies and safety were evaluated 6 and 9 weeks after the treatments.[Results]A mean reduction in lesion count was observed,statistically significance differenc-es in effectiveness were found among each group(P<0.05),the effective ratio was 83.8% in treated group,of which was 61.1% in control group,it showed significant difference between these two groups(P<0.05). There was no side effect.[Conclusion]1 064 nm Q-switched laser combined with drug therapy has a marked effect on mild to moderate rosacea,it is safe and effective,better than simple drug treatment.

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